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July 5, 2013--------News ArchiveLatest research covered daily, archived weekly

Found, gene that controls aggressive breast cancer cells
In a discovery that sheds new light on the aggressiveness of certain breast cancers, Whitehead Institute researchers have identified a transcription factor, known as ZEB1, that is capable of converting non-aggressive basal-type cancer cells into highly malignant, tumor-forming cancer stem cells (CSCs).

Scientists identify molecular switch that kick starts formation of arteries
The findings reveal underlying events that distinguish arteries from veins. Precisely what drives this commitment, which is essential for shaping cardiovascular development, has long eluded researchers. Now, scientists at the Gladstone Institutes have identified the molecular signals that direct this process. In so doing, they illustrate how even the most complex of biological systems can be directed by the most subtle shifts in molecular signaling.

Exercise rescues mutated neural stem cells
CHARGE syndrome* is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the broad spectrum of characteristic CHARGE symptoms has been a mystery.

July 4, 2013--------News ArchiveLatest research covered daily, archived weekly

Key gene's discovered for building the developing brain
Researchers have pinpointed the role of a gene known as Arl13b in guiding the formation and proper placement of neurons in the early stages of brain development.

Scientists discover how human stem cells network
Scientists have discovered a molecular network in human embryonic stem cells (hESCs) that integrates cell communication signals to keep the cell in its stem cell state.

Blocking alzheimer’s, atherosclerosis and type-2 diabetes
Findings suggest there may be one therapeutic target for multiple diseases.Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer’s, atherosclerosis, and type-2 diabetes.

July 3, 2013--------News ArchiveLatest research covered daily, archived weekly

IVF increases small risk for mental retardation
In a study that included more than 2.5 million children born in Sweden, compared with spontaneous conception, any in vitro fertilization (IVF) treatment was not associated with autistic disorder but was associated with a small but statistically significantly increased risk of mental retardation.

Liver protein crucial to pregnancy
A protein first shown to function in the liver plays a crucial role in pregnancy in mice and has a key role in the human menstrual cycle, according to researchers at the University of Montreal.

Taste genes play crucial role in male sterility
Scientists from the Monell Center report the surprising finding that two proteins involved in oral taste detection also play a crucial role in sperm development.

July 2, 2013--------News ArchiveLatest research covered daily, archived weekly

Gene mutations from Dad's lifestyle inheritable for generations
Gene mutations caused by a father's lifestyle can be inherited by his children, even if those mutations occurred before conception.

Research discovers new regulatory autism gene
A new study reports that RORA, a candidate gene for autism discovered in 2010 by the same lab, regulates at least six other genes associated with autism.

How placental cells may prevent viruses from passing from mother to baby
Cells of the placenta have a unique ability to prevent viruses from crossing from an expectant mother to her growing baby and can transfer that trait to other kinds of cells.

July 1, 2013--------News ArchiveLatest research covered daily, archived weekly

Antibacterial soaps may harm nursing babies
A mother's prolonged use of antibacterial soaps containing the chemical triclocarban may harm nursing babies, according to a recent study from the University of Tennessee, Knoxville.

Type 2 diabetic bone marrow stem cells reduce insulin use
A study has found patients receiving self-donated — autologous — transplanted bone marrow stem cells require less insulin following cell transplantation.

'Protein origami' helps us understand, prevent disease
Scientists using sophisticated imaging techniques have observed a molecular protein folding process that may help medical researchers understand and treat diseases such as Alzheimer's, Lou Gehrig's and cancer.


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