Welcome to The Visible Embryo

Home- - -History-- -Bibliography- -Pregnancy Timeline- --Prescription Drugs in Pregnancy- -- Pregnancy Calculator- --Female Reproductive System- News Alerts -Contact

Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.

WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!




Pregnancy Timeline

Prescription Drug Effects on Pregnancy

Pregnancy Calculator

Female Reproductive System

Contact The Visible Embryo

News Archive
Disclaimer: The Visible Embryo web site is provided for your general information only. The information contained on this site should not be treated as a substitute for medical, legal or other professional advice. Neither is The Visible Embryo responsible or liable for the contents of any websites of third parties which are listed on this site.
Content protected under a Creative Commons License.

No dirivative works may be made or used for commercial purposes.

Return To Top Of Page
Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
Search artcles published since 2007

October 9, 2012--------News Archive Return to: News Alerts

The implications of the research are far reaching, from new approaches to learning
and language acquisition, to new considerations for the health effects of social
environments affecting large populations, and policies for
early childhood care and education.

WHO Child Growth Charts


Developmental Neuroscience – A New Field Changing Understanding of Childhood

By the time our children reach kindergarten their learning and developmental patterns are already taking shape, as is a trajectory for their future health

Now, for the first time, scientists have amassed a large collection of research that looks "under the skin", to examine how and why experiences interact with biology starting before birth to affect a life course.

Biological Embedding of Early Social Adversity: From Fruit Flies to Kindergartners, a special volume published in the Proceedings of the National Academy of Sciences and authored largely by researchers of the Canadian Institute for Advanced Research (CIFAR), sets out an emerging new field of the developmental science of childhood adversity.

The implications of the research are far reaching, from new approaches to learning and language acquisition, to new considerations for the health effects of social environments affecting large populations, and policies for early childhood care and education.

"CIFAR's multidisciplinary and international program in early childhood development is transforming our understanding of how early life experiences affect the development of the brain and in so doing set a lifelong trajectory," says Dr. Alan Bernstein, CIFAR President & CEO. "This research is providing the scientific basis for public policy concerning the critical window to provide the optimal conditions that will enable our children to grow up to be well-adjusted, well-educated and productive individuals."

The volume is a multidisciplinary collection of 25 thought-provoking papers that have implications for a broad range of scientific inquiry: from molecular genetics, evolutionary biology and neuroscience to social and behavioural science, epidemiology and social policy.

"This is the first volume of collected research to provide such a substantial and comprehensive picture of the interaction between experience and biology in the early years," says Dr. Marla Sokolowski, Co-director of CIFAR's program in Experience-based Brain & Biological Development, and Co-editor of the PNAS volume. "Brain and genetic development are extraordinarily intricate and complex, and so by approaching this question from multiple angles, we're able to reveal a convergence on a number of themes, giving us new insights and an understanding of a greater whole, which now sets more clearly a direction for research to come."

Select highlights:

From the lab of CIFAR Fellow Michael Meaney (McGill University):

Scientists have provided evidence that socioeconomic status affects family function and the development and function of brain regions that are critical for attention, learning and memory.

Meaney’s lab looks into how parenting produces lasting effects on cognitive and emotional development. His lab examined development in rats and found parental influences on the chemical, or 'epigenetic', signals that control the activity in the brain of genes that influence the connections between brain cells as well as learning and memory.

In adult animals that were licked more frequently by their mothers the epigenetic signals enhanced the activity of genes associated with learning and memory.

These findings reveal that social influences during early life affect the activity of genes that affect the structure and function of brain regions critical for cognitive capacity.

From the lab of CIFAR Fellow Takao Hensch (Harvard University):

Given that music is a powerful tool for probing and promoting brain development, Hensch and his collaborators exposed young mice to music and discovered a critical period between 15 and 24 days of life when they could change the mice's innate preference for a silent shelter to a preference for shelter with music.

Typically, this preference cannot be altered in adulthood. However, the team then treated adult mice and were able to show that a key brain region could be re-wired to have a preference for music in later adult years.

His results point to molecular factors that emerge after early critical periods of plasticity and can be manipulated in adulthood – the first evidence that a juvenile form of higher cognitive behavior can be restored.

This clearer picture of molecular mechanisms in early development is critical to eventually treating complex, life-long disorders of the brain, such as autism or acute anxiety.

From the lab of CIFAR Fellow W. Thomas Boyce (University of British Columbia):

Guided by animal models of hierarchy and an understanding of the health effects of socioeconomic status (SES), Tom Boyce and his team examined the behavioral development of children in a kindergarten classroom hierarchy.

The study found that children in subordinate roles had more depressive behaviors and inattention, fewer good friends and diminished academic ability. The study found that subordination was compounded by low SES – the children with low SES had the lowest levels of prosocial behaviors.

Importantly, the study found that teachers who utilized child-centred teaching practices to create better classroom climates were able to diminish some of the adverse effects of stratification.

The study suggests that socioeconomic gradients in health and development are the products of more than simply differences in access to money, material goods, medical care, or nutrition.

When taken with our growing understanding of the importance of the first five years of life, this research renders even more crucial the need to provide egalitarian and supportive early childhood settings.

From the lab of CIFAR Fellow Janet Werker (University of British Columbia), the Child & Family Research Institute (CFRI) at BC Children’s Hospital and Harvard University:

Janet Werker and her research collaborators studied babies belonging to three groups of mothers –

One being treated for depression with serotonin reuptake inhibitors (SRIs),

One with depression not taking antidepressants and

One with no symptoms of depression.

By measuring changes in heart rate and eye movement to sounds and video images of native and non-native languages, the researchers calculated the language development of babies at three intervals, including six and 10 months of age.

The heart rate response of unborn babies at age 36 weeks to languages was also measured. Their study is the first to show that maternal depression and its treatment can accelerate babies’ ability to attune to the sounds and sights of their native language, thereby affecting the timing of language development in babies.

About CIFAR's program in Experience Based Brain & Biological Development

Launched in 2003, CIFAR's research program in Experience-based Brain and Biological Development explores the core question of how social experiences and settings affect developmental biology and help set early trajectories of lifelong development and health.

The CIFAR research program brings together an international team of scientists with expertise in neurobiology, molecular genetics, epidemiology, developmental sciences, pediatrics and psychology. Their work capitalizes on new techniques for measuring physiological changes, as well as a new abundance of knowledge in genetics, epigenetics, and neuroscience.

This breadth and interdisciplinarity has led to transformative new thinking in understanding gene-environment interactions: CIFAR researchers say the nature-versus-nurture debate is dead. Real solutions come from studying interactions between the two.

In December, 2011, members of CIFAR's Experience-Based Brain & Biological Development program partnered with the NAS to present the Arthur M. Sackler Colloquium of the National Academy of Sciences, "Biological Embedding of Early Social Adversity: From Fruit Flies to Kindergartners," which became the genesis for this PNAS volume. Thomas Boyce and Marla Sokolowski are co-directors of CIFAR’s Experience-based Brain & Biological Development program, as well as the co-editors of the PNAS special edition.

CIFAR researchers reporting in the PNAS special edition

Ronald G Barr (University of British Columbia): Abusive head trauma: Preventing a failure of normal caregiver-infant interaction.

W. Thomas Boyce (University of British Columbia): Social stratification, classroom 'climate' and the behavioral adaptation of kindergarten children.

David F Clayton (Queen Mary, University of London): The impact of experience-dependent and -independent factors on gene expression in songbird brain.

Lia C. H. Fernald (University of California at Berkeley): Socio-economic gradients in child development in very young children: Evidence from India, Indonesia, Peru and Senegal.

Russell D Fernald (Stanford University): How does social information change the brain?

Takao K Hensch (Harvard): A critical period for acoustic preference in mice.

Clyde Hertzman (University of British Columbia): Biological embedding: Putting the concept in perspective.

Michael S Kobor (University of British Columbia): Biological and environmental predictors of variable DNA methylation in a human community cohort.

Bryan Kolb (University of Lethbridge): Experience and the developing prefrontal cortex.

Joel D. Levine (University of Toronto, Mississauga): Social structures depend on innate determinants and chemosensory processing in Drosophila.

Michael J. Meaney (McGill University and Douglas Hospital Research Centre): Variations in postnatal maternal care and the epigenetic regulation of Grm1 expression and hippocampal function in the rat.

Michael Rutter (King's College London): Achievements and challenges in the biology of environmental effects.

Marla B Sokolowski (University of Toronto): Gene-environment interplay in Drosophila melanogaster: Chronic food deprivation in early-life affects adult exploratory and fitness traits.

Moshe Szyf (McGill University): Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus.

Janet F. Werker (University of British Columbia): Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception.

Original article: http://www.eurekalert.org/pub_releases/2012-10/cifa-anf100212.php