|Home-- -History-- -Bibliography- -Pregnancy Timeline- --Prescription Drugs in Pregnancy- -- Pregnancy Calculator- --Female Reproductive System- -Contact|
Click weeks 0 - 40 and follow fetal growth
TET1 Crucial to Fetal Development and Cancer
Aging Eggs Key to Miscarriage and Birth Defects
Female Body Basis for Medical Autopsy/Dissection
A Measure of Cell Health - The Length of Telomeres
Stress In Pregnancy May Create Obesity in Child
Umbilical Cord Stem Cells Studied for Lupus Therapy
Dopamine Controls Formation of New Brain Cells
Untangling The Complexity Of The Brain
New Treatment for Rare Recurrent Fever in Kids
children monitored from birth, children with high levels of a pollution exposure marker in their cord blood had more attention problems and anxiety/depression at ages 5 and 7 than children with lower exposure.
The study by researchers at the Columbia Center for Children's Environmental Health (CCCEH) and the Institute of Cancer Research in England is the first to examine the behavioral effects of prenatal exposure to these air pollutants in children using a biologic marker.
The researchers measured a biologic marker or "fingerprint" of exposure to polycyclic aromatic hydrocarbons (PAH) and other combustion-related pollutants in newborns' cord blood.
When inhaled by the mother during pregnancy, these pollutants can be transferred across the placenta and bind to the DNA of the fetus, forming "adducts" in blood and other tissues and providing a biologic measure of pollutant exposure. Mothers completed a detailed assessment of their child's behavior.
In urban air, traffic emissions are a dominant source of the pollutants measured in the study. The authors accounted for other sources such as environmental tobacco smoke and diet in their analyses. None of the mothers in the study were smokers.
"The results are of potential concern since attention problems and anxiety and depression may affect subsequent academic performance as well as peer relationships and other aspects of societal functioning," said Dr. Frederica Perera, the study's lead author and Center Director.
"Fortunately, it is possible to reduce these air pollutants through currently available pollution controls, energy efficiency, and alternative energy sources."
"PAH/Aromatic DNA Adducts in Cord Blood and Behavior Scores in New York City Children," is published in Environmental Health Perspectives online April 12, 2011 and is to be released in an upcoming print issue.
Funding for the study was provided by NIEHS, the EPA and private foundations.