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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.

WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!




Pregnancy Timeline

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Disclaimer: The Visible Embryo web site is provided for your general information only. The information contained on this site should not be treated as a substitute for medical, legal or other professional advice. Neither is The Visible Embryo responsible or liable for the contents of any websites of third parties which are listed on this site.
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Pregnancy Timeline by SemestersFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresFemale Reproductive SystemEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterSecond TrimesterFirst TrimesterFertilizationDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
Google Search artcles published since 2007
September 30, 2011--------News Archive

Estrodial A Unisex Hormone Essential To Metabolism
Possible treatment options could result for diabetes, obesity and heart disease.

Remove Fibroids - Prevent Recurrent Miscarriages
Research has found the first, firm evidence that fibroids are associated with recurrent miscarriages.

Understanding How Brain White Matter Develops
Study findings indicate a key step in the generation of white matter and understanding developmental disabilities.

'Alarm Clock' Gene Wakes-Up Biological Clock
Finding promises insight into sleeplessness, aging and chronic illness, such as diabetes and cancer.

September 29, 2011--------News Archive

Control Gene for Developmental Timing Discovered
Research has identified a key regulator controlling the speed of development in fruit flies. Blocking this regulator sped up the animals' rate of maturity.

Low Zinc/Copper Might Cause Spontaneous Abortion
This hypothesis had never been proven before in humans, and now has been demonstrated by University of Granada research.

Scientists Identify New Brain Stem Cell Activity
Finding raises questions of how the human brain develops and evolves.

Millesecond Memory
'Teleportation' of rats sheds light on how the memory is organized.

September 28, 2011--------News Archive

What Do Infants Remember, What Do They Forget?
In fact, they understand that objects once seen, should not disappear.

Found: New Gene Region for Testicle Development
Research has found a new genetic region which may control testicle development in the foetus.

September 27, 2011--------News Archive

Severe/Moderate Preemie Lung Function Improves
The negative effects of premature birth, whether moderately premature or extremely so, may be reversed by their teenage years.

Mom's Exercise Protects Baby From Alzheimer's
New research suggests prenatal exercise improves brain plasticity, decreases toxic protein deposits, inflammation and oxidative stress, warding off Alzheimer's.

Predicting the Best Treatment for Breast Cancer
Researchers identify new genes that help determine breast cancer prognosis.

September 26, 2011--------News Archive

Key Step Reprograms Adult Cells to Mimic Stem Cells
UNC researchers identify an important difference in sperm cell reprogramming needed to initiate formation of the embryo.

First USA Embryonic Stem Cell Therapy for Paralysis
The trial is being run by Geron Corp. of Menlo Park, Calif., which developed and manufactures the cells being tested.

UK Begins Stem Cell Trial for Disorder of the Retina
A new clinical trial using retinal cells derived from stem cells will treat people with an inherited eye condition which causes loss of sight in young people.

Pregnancy Occupation Can Cause Asthma in Child
Mothers who are exposed to particular agents during pregnancy could give birth to children with a higher risk of asthma, according to new research.

WHO Child Growth Charts

Mature muscle fibers were marked to glow green.

Image by Su-Chun Zhang, neurodevelopmental biologist at the Waisman Center.
courtesy Wisconsin Alumni Research Foundation. August 2001

By Krista Conger

The Stanford University School of Medicine and Santa Clara Valley Medical Center have enrolled the fourth participant in the nation’s first trial of cells derived from human embryonic stem cells. The phase-1, FDA-approved trial is meant to test the safety of the cells in up to 10 people with recent spinal cord injuries at seven trial sites across the United States.

The most recent patient was treated Sept. 17 at the Rehabilitation Trauma Center at SCVMC with cells prepared for injection at Stanford. Stanford neurosurgeon Gary Steinberg, MD, PhD, implanted the cells. Three other patients have previously received the surgically delivered cells: two at the Shepherd Center in Atlanta beginning in October of last year, and one at Northwestern Memorial Hospital and the Rehabilitation Institute of Chicago in May 2011. The Stanford/SCVMC patient is the first person to receive the therapy west of the Mississippi.

“We are extremely excited to participate in this landmark clinical trial,” said Steinberg, who is the Bernard and Ronni Lacroute-William Randolph Hearst Professor in Neurosurgery and Neurosciences at Stanford and the principal investigator of the Stanford/SCVMC portion of the trial. “It signifies a major advance in translating an innovative research discovery into clinical therapy. I believe it is critically important to encourage and take part in stem cell trials like this, which represent a new era in the effort to restore function for patients with stroke, brain injury, Parkinson’s disease and other devastating neurologic disorders.”

Those sentiments were echoed by Stephen McKenna, MD, chief of the rehabilitation center at SCVMC. “It has been an extraordinarily collaborative process at every step, from developing the screening process and identifying possible patients to evaluating these patients for surgery,” McKenna said. “Although it’s been an intensive commitment of resources, we understand the importance of advancing new therapies for patients.”

The trial is being run by Geron Corp. of Menlo Park, Calif., which developed and manufactures the cells being tested. In May, Geron received a $25 million grant from the California Institute for Regenerative Medicine to continue and extend the trial to include a greater proportion of spinal cord injuries.

“When the people of California voted in favor of Proposition 71, they did so with the hope of seeing stem-cell-based therapies for chronic disease and injuries. This first California patient to participate in Geron’s landmark spinal cord injury trial is a major step toward fulfilling that hope,” said Jonathan Thomas, chair of the CIRM governing board.

“We are proud to be providing funding for this first safety trial, which is a critical step toward making safe and effective stem-cell-based therapies available to patients.”

Researchers at Geron collaborated with Hans Keirstead, PhD, and his laboratory team at UC-Irvine to develop a way to coax human embryonic stem cells to become a mixture of cells that include oligodendrocyte precursors. Oligodendrocytes are cells in the brain and the central nervous system that wrap nerve cells with an insulating material called myelin. This myelin sheath is necessary for the transmission of the electric signals along the spinal cord that trigger muscles to move, and relay our sense of touch and temperature. Damage to this sheath caused by trauma is a common cause of paralysis.

To be eligible for the trial, patients must have recent (within 14 days of injury) non-penetrating damage to a specific region of their thoracic spine — an area roughly from the top of the shoulder blades to the bottom of the rib cage. The damage must cause complete paraplegia, meaning that they have normal sensation or movement to the level of the hands, but not from the trunk to the toes.

During the procedure, Steinberg applied about 2 million of the special cells, called GRNOPC1, directly into the injured area of the patient’s spinal cord.

“We are quite pleased that the surgery was completed successfully and the patient is doing well,” said Steinberg.

Following the surgery at SCVMC, the patient entered an intensive inpatient rehabilitation program under the supervision of McKenna and James Crew, MD, who are specialists in spinal cord injury medicine. Researchers will now monitor the patient for any adverse events to confirm that the cells are safe for use in humans.

“In the future, cellular therapies such as those used today will open new hopes for a cure to catastrophic neurological injuries,” said McKenna. “Our institution is the first rehabilitation hospital in the western United States delivering human embryonic stem cell treatments for spinal cord injury. Kaiser Permanente demonstrated a strong commitment to research by transferring the patient to Valley Medical Center where this trial is being conducted.”

In June, Geron reported preliminary results of the trial on the first two patients at two meetings: the 2011 International Conference on Spinal Cord Medicine and Rehabilitation and the 2011 Spine Symposium. The results so far show no significant adverse effects experienced by either patient. If this phase-1 trial of 10 patients shows that the treatment is safe, future trials will be designed to determine whether the cells are able to improve participants’ clinical symptoms.

Original article: http://med.stanford.edu/ism/2011/september/geron.html