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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Pregnancy Timeline by SemestersFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresFemale Reproductive SystemEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterSecond TrimesterFirst TrimesterFertilizationDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
Google Search artcles published since 2007
 
September 30, 2011--------News Archive

Estrodial A Unisex Hormone Essential To Metabolism
Possible treatment options could result for diabetes, obesity and heart disease.

Remove Fibroids - Prevent Recurrent Miscarriages
Research has found the first, firm evidence that fibroids are associated with recurrent miscarriages.

Understanding How Brain White Matter Develops
Study findings indicate a key step in the generation of white matter and understanding developmental disabilities.

'Alarm Clock' Gene Wakes-Up Biological Clock
Finding promises insight into sleeplessness, aging and chronic illness, such as diabetes and cancer.

September 29, 2011--------News Archive

Control Gene for Developmental Timing Discovered
Research has identified a key regulator controlling the speed of development in fruit flies. Blocking this regulator sped up the animals' rate of maturity.

Low Zinc/Copper Might Cause Spontaneous Abortion
This hypothesis had never been proven before in humans, and now has been demonstrated by University of Granada research.

Scientists Identify New Brain Stem Cell Activity
Finding raises questions of how the human brain develops and evolves.

Millesecond Memory
'Teleportation' of rats sheds light on how the memory is organized.

September 28, 2011--------News Archive

What Do Infants Remember, What Do They Forget?
In fact, they understand that objects once seen, should not disappear.

Found: New Gene Region for Testicle Development
Research has found a new genetic region which may control testicle development in the foetus.

September 27, 2011--------News Archive

Severe/Moderate Preemie Lung Function Improves
The negative effects of premature birth, whether moderately premature or extremely so, may be reversed by their teenage years.

Mom's Exercise Protects Baby From Alzheimer's
New research suggests prenatal exercise improves brain plasticity, decreases toxic protein deposits, inflammation and oxidative stress, warding off Alzheimer's.

Predicting the Best Treatment for Breast Cancer
Researchers identify new genes that help determine breast cancer prognosis.

September 26, 2011--------News Archive

Key Step Reprograms Adult Cells to Mimic Stem Cells
UNC researchers identify an important difference in sperm cell reprogramming needed to initiate formation of the embryo.

First USA Embryonic Stem Cell Therapy for Paralysis
The trial is being run by Geron Corp. of Menlo Park, Calif., which developed and manufactures the cells being tested.

UK Begins Stem Cell Trial for Disorder of the Retina
A new clinical trial using retinal cells derived from stem cells will treat people with an inherited eye condition which causes loss of sight in young people.

Pregnancy Occupation Can Cause Asthma in Child
Mothers who are exposed to particular agents during pregnancy could give birth to children with a higher risk of asthma, according to new research.

WHO Child Growth Charts

Researchers at Wake Forest Baptist Medical Center have made a discovery bringing them closer to predicting the best course for surviving breast cancer.

The group has identified 16 genes, or proteins, all involved in iron metabolism, that provide better prognostic information than conventional, standard markers of prognosis.

Last summer, some of the same investigators published a study showing that women who had high levels of a protein called ferroportin – the only known protein to eliminate iron from cells – and low levels of another protein, called hepcidin, had the best prognosis, or chance of survival without recurrence.

Low levels of ferroportin and high levels of hepcidin were found to be associated with the most aggressive and recurring cancers. Both proteins are involved in the body's metabolism of iron, a key food source for cancerous cells.

The finding suggested that testing for ferroportin levels in women with breast cancer may one day help doctors to more accurately predict whether their patients' cancers will return. It may also help some women with high levels of the protein to avoid invasive or toxic treatments such as chemotherapy.

Building upon that information, the researchers set out to evaluate other proteins involved in iron metabolism and determine if they provide any prognostic value for breast cancer patients, as well.

As it turns out, they do.

The study, supported by the National Institutes of Health, is now available online in Cancer Research.

"We're really interested in trying to understand, at a deeper functional level, what these genes are doing," said Frank Torti, M.D., MPH, director of the Comprehensive Cancer Center at Wake Forest Baptist and senior investigator on the paper.

"Many of these genes have been discovered because they have something to do with body iron management, but they haven't really been studied in tumor development, and we know that tumors are iron consumers. There's a lot still left to understand about the function of these genes in breast tissue, but we're finding out that iron, and how it's metabolized, has a whole lot to do with cancer."

The researchers looked at 61 genes involved in iron regulation to see how many of them were related to breast cancer prognosis and found that almost half were. They next narrowed those genes down even further to a subset of 16 that are most closely associated with prognosis.

"Ferroportin and hepcidin aren't the only iron-regulating genes playing a role in breast cancer," Torti said. "As it turns out, many iron genes are associated with breast cancer outcomes. These 16, we've discovered, convey the most valuable information."

Within this group of 16 genes, called the Iron Regulatory Gene Signature, Torti and colleagues found that there are several pairings, called dyads, that work together to regulate iron in a cell. Ferroportin and hepcidin, the original gene dyad found, control iron export.

Now, they have found that an additional pair of genes that control iron import, called transferrin receptor and HFE, is also important. Understanding how changes in those relationships affect breast cancer prognosis is the focus of the team's future research.

"There's a growing understanding that tumor cells have an altered metabolism," Torti said. "We know that they consume sugar and fats in different ways. These findings now show that tumor cells also handle iron in different ways from non-cancer cells, and that this has important consequences for patient prognosis. There are more genes in the Iron Regulatory Gene Signature whose function in breast cancer we don't fully understand, so there's certainly more discovery to be done.

All of this work and new information will help us be able to better predict prognosis for breast cancer patients and hopefully, one day, will help guide our treatment recommendations."

Co-authors on the study are lead author Lance D. Miller, B.S., M.S., Ph.D., Lan G. Coffman, M.D., Ph.D., Jeff W. Chou, Ph.D., Ralph D'Agostino Jr., Ph.D., and Torti's co-lead investigator Suzy V. Torti, Ph.D., all of Wake Forest Baptist; Michael A. Black, of the Otago School of Medical Sciences, New Zealand; and Jonas Bergh, of the Cancer Center Karolinska, Stockholm.

Wake Forest Baptist Medical Center (www.wakehealth.edu) is a fully integrated academic medical center located in Winston-Salem, N.C. Piedmont Triad Research Park, a division of Wake Forest Baptist, fosters biotechnology innovation in an urban park community. Wake Forest Baptist Health, the clinical enterprise, includes a flagship tertiary care hospital for adults, Brenner Children's Hospital, a network of affiliated community-based hospitals, physician practices and outpatient services. The institution's clinical programs and the medical school are consistently recognized as among the best in the country by U.S.News & World Report.

Original article: http://www.eurekalert.org/pub_releases/2011-09/wfbm-rin092611.php