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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
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November 4, 2011--------News Archive

Identifying Brain Cells That Keep Us Awake
Researchers at UCLA have identified the group of neurons that mediates whether light arouses us — or not.

TBL1X Gene Involved In Autism Spectrum Disorder
An X-chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males.

“Love Hormone” Helps Direct Development of Brain
Hormones released from nerves regulate a series of vital body processes, including the balance of fluids and uterine contractions in childbirth.

November 3, 2011--------News Archive

Steroids in Preemies Impair Brain Growth
Premature infants given drugs to support lung maturation and normalize blood pressure, are at increased risk for having impaired growth of the cerebellum.

Potential Treatment for Sickle Cell Disease
Increasing the expression of proteins TR2/TR4 can lead to higher fetal hemoglobin levels in sickle cell patients.

New Drug Shows Promise Against Multiple Sclerosis
A new drug targets a molecule - CD20 found on the surface of B cells and B cells seem to induce the immune system T cells to attack.

November 2, 2011--------News Archive

Babies Understand Each Other at Ten Months Old
At 10 months, babies start to understand another person’s thought process, providing new insights on how communication develops.

Bacteria Swap Genes Between Species Readily
Microbes have developed a quick and effective way to exchange genetic information from animals to humans.

Pinpointing Cause of Unexplained Miscarriage
The same kind of blood-clotting in coronary arteries or blood vessels in the brain which causes heart attacks and strokes also happens in the placenta.

November 1, 2011--------News Archive

Pregnant Mothers At Risk From Air Pollution
A Californian-based study has looked in detail at air quality and the impact of traffic-related air pollution on premature birth.

Linking A Spectrum of Childhood Diseases
An international collaboration of scientists has identified a genetic mutation causing a rare childhood disease characterized by inflammation and fat loss.

Placenta and Uterus Battle Becomes Preeclampsia
A battle brews in the mother’s womb between the father’s biological goal to produce the biggest, healthiest baby possible vs. the mother’s need to live through delivery.

October 31, 2011--------News Archive

Fetal Heart Rate Not a Good Indicator for Health
Maternal-fetal medicine specialists at Intermountain Medical Center seek better 'road map' to improve deliveries, healthier babies.

Swedish Discover Bisphenol A Affects Newborn Brain
An observed effect induced in neonatal baby mice after exposure to Bisphenol A, persisted into adulthood.

Not Your Mother's Birth Control
Today's hormonal forms of birth control are vastly different from those used by earlier generations of women, both with lower levels of hormones and with different means of delivery (not just a pill), but many of the same problems related to women's pleasure remain.

WHO Child Growth Charts

Newborn mice that are exposed to Bisphenol A develop changes in their spontaneous behavior and display poorer adaptation to new environments, as well hyperactivity as young adults. This has been shown by researchers at Uppsala University. Their study also revealed that one of the brain’s most important signal systems, the cholinergic signal system, is affected by Bisphenol A and that the effect persisted into adulthood.

Our environment contains a number of pollutants, including Bisphenol A, which is used in plastics in a number of different applications. When plastic products are used, Bisphenol A can leak out, which is especially problematic as it is used in baby bottles, tin cans, plastic containers, plastic mugs, which are used by people of all ages. Both in Sweden and globally, Bisphenol A is widely used, and the substance has been found in human placentas, fetuses, and breast milk.

In recent years measurable amounts of Bisphenol have been found in dust from regular homes, but opinion differs regarding any negative effects of Bisphenol A, and risk assessments from various parts of the world present contradictory recommendations, even though the information used comes from the same research reports. Here in Sweden the Swedish Chemicals Agency and the Medical Products Agency are working on a ban for Bisphenol A in baby bottles and certain other plastic products.

In humans and mammals, the brain develops intensively during a limited period of time. In human babies, this brain development period runs from the seventh month of gestation through the first two years of life. The corresponding period for mice takes place during the 3-4 first weeks after birth. Uppsala researchers have shown in previous research studies that various toxic compounds can induce permanent damage to brain function when they are administered to newborn mice during this developmental period. Examples of such compounds are so-called brominated flame-retardants, polychlorinated biphenyls (PCBs), and DDT.

In an entirely new study these researchers examined whether exposure to Bisphenol A during the neonatal period can cause permanent damage to brain function. In the experiment different doses of Bisphenol A were given to mice when they were ten days old. The mice underwent a so-called spontaneous behavior test as young adults, in which they were made to change cages from their well-known home cage to another identical one during one hour. Normal mice are very active during the first 20 minutes, exploring the new home environment. This activity declines during the next 20 minutes, and in the final 20 minutes it drops even more, and the mice settle down and sleep.

“In our study we found that a single exposure to Bisphenol A during the short critical period of brain development in the neonatal period leads to changes in spontaneous behavior and poorer adaptation to new environments, as well as hyperactivity among young adult mice. When this is examined again later in their adult life, these functional disturbances persist, which indicates that the damage is permanent and do not in fact disappear,” says Henrik Viberg at the Department of Organism Biology.

Using the same behavioral method, it was also examined whether the individuals that had received Bisphenol A during their neonatal period reacted differently than normal individuals to adult exposure to nicotine, which would indicate that one of the brain’s most important signal systems, the cholinergic signal system, was affected. Normal animals exposed as adults to the given dose of nicotine experience dramatically increased activity compared with animals that were not exposed to nicotine. Animals that had been exposed to Bisphenol A during their neonatal period and then received nicotine as adults did not evince the same hyperactivity as normal animals at all. This indicates that the choligernic signal system had been affected and that these individuals had had developed increased sensitivity to this type of exposure in adulthood. Once again, this effect was induced during the neonatal period but persisted into adulthood.

“We have previously seen this type of effect from several other environmental toxins that are still prevalent in both indoor and outdoor environments. As these effects are similar to each other, it’s possible that several different environmental toxins, including Bisphenol A, may work together in causing disturbances during brain development. This in turn may mean that the individual dosages of the various environmental toxins that are required to cause disturbances may be lower than those we examined in our studies of, for example, Bisphenol and brominated flame-retardants,” says Henrik Viberg.

This research is published in the scientific journal Toxicology: Dose-dependent behavioral disturbances after a single neonatal Bisphenol A dose, Toxicology, In Press, Uncorrected Proof, Henrik Viberg, Anders Fredriksson, Sonja Buratovic, Per Eriksson
doi:10.1016/j.tox.2011.09.006

Original article: http://www.uu.se/en/news/news-document/?id=1515&area=2,3,10,16&typ=pm&na=&lang=en&fromSiteNodeId=39806