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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Disclaimer: The Visible Embryo web site is provided for your general information only. The information contained on this site should not be treated as a substitute for medical, legal or other professional advice. Neither is The Visible Embryo responsible or liable for the contents of any websites of third parties which are listed on this site.
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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
Google Search artcles published since 2007
 
November 11, 2011--------News Archive

Pre-birth Brain Growth Problems Linked to Autism
A small, preliminary study provides direct evidence for possible prenatal causes of autism.

Poor 1st, 3rd Trimester Sleep Linked to Early Births
Improving mother’s sleep habits through early intervention could reduce risk.

November 10, 2011--------News Archive

Possible New Target for Treating Kids' Liver Disease
An unexpected discovery in an often lethal pediatric liver disease may lead to a new therapy for the hard-to-treat condition.

Diagnoses of Autism Spectrum Disorders Vary Widely
Study suggests common diagnostic subcategories like asperger syndrome are flawed are of questionable value.

November 9, 2011--------News Archive

Single Protein Causes Varicose Veins
Scientists have developed a model for studying varicose veins. Their hope is that drugs can be developed to decelerate or even prevent new varicose veins.

"Switching On/Off" of Brain Genes Throughout Life
The “switching on” or expression of specific genes in the human makes each human being unique. The On/Off switching of brain cells continues throughout life.

Balancing Male and Female X Genes
Cells use 'mathematics' to equalize the loss of an X chromosome gene in males.

November 8, 2011--------News Archive

MRI Reveals Injuries in Developing Brain
New research supports the potential of high-field MRI for early identification of tiny brain injuries in the preterm infant.

Epigenetic Signatures of Autism
Analysis reveals overlap between genetic and epigenetic risk maps in autism.

November 7, 2011--------News Archive

"Cat Litter" Disease Alters Brain Chemistry
Infection by the brain parasite Toxoplasma gondii, directly affects the production of dopamine in the brain.

Two Molecules That Kill Lymphoma Cells In Mice
Two molecules have been identified that may be more effective as lymphoma cancer killers than anything currently available on the market.

Why Some Children Became Critically Ill in 2009 Flu
The largest study to date finds that kids co-infected with MRSA had an increased death risk of 8-fold. Flu vaccination is strongly urged!

WHO Child Growth Charts

Scientists at the University of Massachusetts Medical School are the first to map epigenetic changes in neurons in the brains of individuals with autism. This research is the first to provide empirical evidence that epigenetic alterations - or changes in gene expression caused by forces other than the underlying DNA sequence - may play an important role in the disease.

Analysis of these variations revealed hundreds of genetic sites that overlap with many of the genetic regions known to confer risk for Autism Spectrum Disorders. The study was published in Online First, Archives of General Psychiatry.

Autism spectrum disorders are a group of complex biological illnesses with a variety of origins. People with a disorder on the autism spectrum often struggle with social interactions and communication. Many suffer from delayed language skills, as well as restricted interests and repetitive behavior. It's estimated that only 10 percent of cases are a result of genetic mutations. The cause of the remaining 90 percent of cases is unknown.

"We know that autism is a biological disorder," said Schahram Akbarian, MD, PhD, director of the Irving S. and Betty Brudnick Neuropsychiatric Research Institute and professor of psychiatry at the University of Massachusetts Medical School.

"But very little is known about the genetic and molecular underpinnings associated with the disorder. It's been hypothesized that an epigenetic model of autism could potentially explain why genetic screening strategies for the disorder have been so difficult and frustrating. Our study is the first clear evidence gained exclusively from nerve cells pointing to a link between epigenetic changes and known genetic risk sites for autism."

In order to see if epigenetic changes were occurring in individuals with autism, Akbarian and colleagues developed a novel method for extracting chromatin – the packaging material that compresses DNA into a smaller volume so it can fit inside a cell's nucleus – from the nuclei of postmortem nerve cells.

Using tissue samples obtained through the Autism Tissue Program from 16 individuals diagnosed with an autism spectrum disorder, Akbarian and colleagues used deep sequencing technology to compare these tissue samples with 16 control samples for changes in histone methylation, a small protein that attaches to DNA and controls gene expression and activity.

After analyzing the sequenced DNA data, Zhiping Weng, PhD, director of the Program in Bioinformatics and Integrative Biology and professor of biochemistry & molecular pharmacology at UMass Medical School, found hundreds of sites along the genome affected by an alteration in histone methylation in the brain tissue from the autistic individuals.

However, less than 10 percent of the affected genes they observed were the result of a mutation to the DNA sequence.

"Neurons from subjects with autism show changes in chromatin structures at hundreds of loci genome-wide, revealing considerable overlap between genetic and epigenetic risk maps of developmental brain disorders," said Akbarian.

"Our understanding of psychiatric disorders, such as autism, is burdened by the fact that we often can't see the structural changes that lead to disease," said Akbarian. "It's only by studying these diseases on the molecular level that scientists can begin to get a handle on how they work and understand how to treat them."

The University of Massachusetts Medical School, one of the fastest growing academic health centers in the country, has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research. The Medical School attracts more than $307 million in research funding annually, 80 percent of which comes from federal funding sources. The mission of the Medical School is to advance the health and well-being of the people of the commonwealth and the world through pioneering education, research, public service and health care delivery with its clinical partner, UMass Memorial Health Care. For more information, visit www.umassmed.edu.

Original article: http://www.eurekalert.org/pub_releases/2011-11/uomm-uri110711.php