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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
Google Search artcles published since 2007
 
November 18, 2011--------News Archive

Increasing Uterine Development Genes Improve IVF
Increasing certain developmental genes at precise times in the uterus might improve pregnancy rates from in vitro fertilization-embryo transfers (IVF-ET).

“Silent” Strokes in Children with Sickle Cell Anemia
Silent strokes are the most common form of neurological injury found in SCA, with more than 25 percent of children with the disorder suffering a SCI by age six and nearly 40 percent by age 14.

Mystery Atom In Enzyme Critical for Life
All life requires the element nitrogen from the atmosphere to form amino acids and build proteins. But how to single out the atom in the middle of the process?

November 17, 2011--------News Archive

Breast-Milk Stem Cells!
Embryonic-like stem cells have been isolated from breast milk in large numbers.

All Mammals Share Common Brain Organization
Animal studies show that the outer layer of the brain – the cortex – is organized by genes which exhibit highly similar regional patterns between species.

3 p.m. Slump? A Sugar Rush Is NOT The Answer
Protein, not sugar, stimulates cells to keep us thin and awake, new study suggests

November 16, 2011--------News Archive

Delayed Cord Clamping Protects Babe from Iron Loss
Waiting for at least three minutes before clamping the umbilical cord in healthy newborns improves their iron levels at four months.

Mom's Brain More Damaged by Alcohol than Dad's
After only four years of problem drinking, a significant decrease in the function of the serotonin system in women's brains can be seen.

Regenerative Medicine
Engineered, Blood Vessels Reverse Anemia in Mice
System combining gene therapy with tissue engineering could avoid the need for frequent injections of recombinant drugs.

November 15, 2011--------News Archive

Parkinson's Risk Great if Exposed Trichloroethylene
Symptoms of disease may appear 10 to 40 years following exposure.

Fetal Placental Stem Cells May Help Maternal Heart
Researchers have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury.

Pituitary-Like Tissue Grown From Mouse Stem Cells
Creating functional, three-dimensional tissue and organs from pluripotent embryonic stem cells (EScs) is one of the grand challenges of stem cell research.

November 14, 2011--------News Archive

Dyslexia Not Tied To Low IQ
Research on brain activity fails to support widely believed expectation that dyslexic students may have lower reading ability.

Intestinal E. coli Can Convert Sugar to Biodiesel Fuel
Biodiesel can be generated using E. coli as a catalyst, which will produce high volumes of the fuel with just a little tweaking of the bacteria's cell controls.

Cooked Food May Account For Human Big Brains
Harvard study finds an increase in energy from meat, suggesting cooking food was key to human evolution.

WHO Child Growth Charts

Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury.

The research, which marks a significant advancement in cardiac regenerative medicine, was presented today at the American Heart Association's (AHA) Scientific Sessions 2011 in Orlando, Florida, and is also published in the current issue of Circulation Research, a journal of the AHA.

In the first study of its kind, the Mount Sinai researchers found that fetal stem cells from the placenta migrate to the heart of the mother and home to the site where an injury, such as a heart attack, occurred. The stem cells then reprogram themselves as beating heart stem cells to aid in its repair. The scientists also mimicked this reprogramming in vitro, showing that the fetal cells became spontaneously beating heart cells in cell culture, which has broad-reaching implications in treating heart disease.

Previous studies have documented a phenomenon in which half of women with a type of heart failure called peripartum cardiomyopathy saw their condition spontaneously recover in the months following pregnancy. Based on this evidence, the Mount Sinai team wanted to determine whether fetal stem cells played a role in maternal recovery.

They evaluated the hearts of pregnant female mice that underwent mid-gestation heart injury and survived. Using green fluorescent protein in the fetuses to tag the fetal stem cells derived from the placenta, they found that the green fluorescent stem cells homed to the injured hearts of their mothers, grafted onto the damaged tissue, and differentiated into smooth muscle cells, blood vessel cells, or another type of heart cell called cardiomyocytes.

"Our research shows that fetal stem cells play an important role in inducing maternal cardiac repair," said Hina Chaudhry, MD, Director of Cardiovascular Regenerative Medicine at Mount Sinai School of Medicine, and principal investigator of the study. "This is an exciting development that has far-reaching therapeutic potential."

With a broader understanding of the role of fetal stem cells, Dr. Chaudhry and her team then isolated the fetal cells that had grafted onto the maternal hearts and recreated the environment in vitro. They found that the cells spontaneously differentiated into cardiac cells in cell culture as well.

Until now, researchers have had limited success in discovering the regenerative potential of stem cells in heart disease. The use of bone marrow cells in cardiac regeneration has largely failed as well. Dr. Chaudhry's research team has found that fetal cells may potentially be a viable therapeutic agent, both through in vivo and in vitro studies.

"Identifying an ideal stem cell type for cardiac regeneration has been a major challenge in heart disease research," said Dr. Chaudhry. "Embryonic stem cells have shown potential but come with ethical concerns. We've shown that fetal stem cells derived from the placenta, which is discarded postpartum, have significant promise. This marks a significant step forward in cardiac regenerative medicine."

These findings have implications beyond cardiovascular disease. The fetal stem cells traveled only to the injury site on the damaged heart, and not to other undamaged organs, meaning research on the benefit of these cells on organs damaged by other diseases would be beneficial. Importantly, a significant percentage of the fetal cells isolated from maternal hearts express a protein called Cdx2, which indicates that the cells may not have developed mature immune recognition molecules and therefore are unlikely to cause a negative immune response, which occurs in organ transplant.

"Our study shows the promise of these cells beyond just cardiovascular disease," said Dr. Chaudhry. "Additionally, this breakthrough greatly underscores the importance of translational research. As a clinician who also has a basic science laboratory, I am in the unique position to assess the needs of my patients, evaluate how they respond to treatment and recover from illness, and bring that anecdotal knowledge to the experiments in my lab."

The research was supported by a grant from the National Institutes of Health (NIH) to Dr. Chaudhry, a scholarship from the NIH to the first author of the study,graduate student Rina Kara, and an American Heart Association medical student fellowship.

Original article: http://www.eurekalert.org/pub_releases/2011-11/tmsh-fsc111411.php