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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
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November 25, 2011--------News Archive

Women at Low Risk Can Safely Choose Birth Style
Women with low risk pregnancies should be able to choose where they give birth, concludes The Birthplace in England national prospective cohort study.

Finger (Mal)formation Function of Desert DNA
Explaining the diversity of leg shapes in the animal kingdom and hereditary defects in finger formation.

Key Molecular Switch for Telomere Extension Foundd
For the first time, a key target for DNA damage is found that must be chemically modified to enable an enzyme thought to play a key role in cancer and aging.

New Role for Gene in Maintaining Steady Weight
Findings may help combat obesity and diabetes.

November 24, 2011--------News Archive

New Facts About Stuttering
Some forms of persistent stuttering are caused by mutations in a gene governing the recycling of old cell parts - not speech.

Preventing Preemie Brain Injury
New advances could eventually help reduce the number of premature babies who develop cerebral palsy, epilepsy or behavioral disorders such as ADHD.

Short Stature May Be Due To a 'Shortage' of Genes
Research suggests that uncommon genetic deletions are associated with short stature.

November 23, 2011--------News Archive

Intestinal Disorder, Preemies and AB Blood Type
Preemies with the AB blood type who develop NEC are nearly three times as likely to die from it as preemies with other blood types.

Babies Fed Fish Before 9 Months Wheeze Less
But pre-natal pain and fever antibiotics taken by mom in pregnancy, or by the baby in the first-week of life, increase risk of "pre-school wheeze."

Physical Activity Improves Quality Of Sleep
People sleep significantly better and feel more alert during the day if they get at least 150 minutes of exercise a week, a new study concludes.

November 22, 2011--------News Archive

Critical Molecules For Hearing/Balance Discovered
Gene-therapy trial will attempt to restore hearing in deaf mice.

Tweaking One Gene Makes Muscles Twice As Strong
Salk scientists and their collaborators find new avenue for treating muscle degeneration in people who can't exercise.

Fruit Fly Intestine Holds Secret to Fountain of Youth
Long-lived fruit flies offer Salk scientists clues to slowing human aging and fighting disease.

November 21, 2011--------News Archive

Nerve Cells Key to making Sense of All of Our Senses
Scientists have unraveled how the brain manages to process complex, rapidly changing, and often conflicting sensory signals and make sense of our world.

Discovery of A New Muscle Repair Gene
Thanks to next-generation DNA sequencing, an international team of scientists have discovered more about the function of muscle stem cells.

Immune System Governs Stem Cell Regeneration
Controlling a stem cell transplant recipient’s immune response may be major key to successful bone regeneration.

WHO Child Growth Charts

An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques.

The work, which was co-led from the University of Leeds' School of Medicine and the Charité, Berlin, is published this week in the journal Nature Genetics.

The researchers investigated several families whose children suffered from a progressive muscle disease. The children developed severe weakness of the body's muscles and the diaphragm - the main breathing muscle - making them dependent on a wheelchair and continuous mechanical ventilation. The children also had to be tube-fed because the esophagus - a muscular tube that transports food from the mouth down into the stomach - did not work properly.

Using state-of the-art, next generation DNA sequencing technology, the scientists initially found a defect in the MEGF10 gene for a large family living in the UK. Further work found mutations in families with a similar condition from Europe and Asia.

Their work means that accurate genetic testing and diagnosis will now be possible for this devastating condition.

The MEGF10 gene normally plays an important function in muscle stem cells. These are also called 'satellite cells', because they are attached to the outer surface of the muscle fibres, where they normally remain silent. If a muscle fibre becomes damaged, the satellite cells become active, start to divide and then fuse with the muscle fibre.

MEGF10 has an important role in this fusion process because it provides the 'gluey' surface for the attachment of the satellite cell.

Since body muscles make up about 40% of our weight and are the largest organ in the body, the muscles need to be maintained during normal life.

MEGF10 also has a role in this regeneration process; failure causes progressive muscle weakness in not only muscles of the body and limbs but also the muscle cells that can be found in the internal organs.

The project directors commented: "These methods enable us to sequence hundreds or even thousands of genes at the same time for an affordable price. This enables clinicians and researchers to discover novel genetic defects even in single patients. This is good news for families with unsolved rare genetic disorders. Many affected patients and their parents, who often have a "diagnostic Odyssey" behind them, may now hope that the cause of their disease will be found in the near future."

Contact: Paula Gould, University of Leeds Communications & Press Office: Tel 44-113-343-8059, email p.a.gould@leeds.ac.uk

The project's joint directors are Professor Markus Schuelke from the NeuroCure Clinical Research Center and the Department of Neuropediatrics of the Charité, and Professor Colin A. Johnson from the Leeds Institute of Molecular Medicine, University Leeds, emphasized the relevance of the new methods for genomic analysis.

The paper, Logan et al. Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD) is published in Nature Genetics 2011 Nov 20, doi: 10.1038/ng.995..

Reference: Stem cell foundation for muscular dystrophy treatment; Thursday, July 14, 2011

Original article: http://www.eurekalert.org/pub_releases/2011-11/uor-nck111811.php