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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Disclaimer: The Visible Embryo web site is provided for your general information only. The information contained on this site should not be treated as a substitute for medical, legal or other professional advice. Neither is The Visible Embryo responsible or liable for the contents of any websites of third parties which are listed on this site.
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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
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Home--History--Bibliography- -Pregnancy Timeline- Prescription Drugs/Pregnancy- Pregnancy Calculator - Reproductive System- -News Alerts

January 6, 2012--------News Archive

Fresh Embryos May Improve Assisted Reproduction
A new study highlights that miscarriage is less likely to occur after the transfer of fresh embryos compared to frozen-thawed embryos.

Air Pollution Link to Diabetes and Hypertension in African-American Women
The risk of diabetes increased by a significant 24 percent, and the risk of hypertension by 11 percent, with increased exposure to nitrogen oxides.

Poor Maternal Diet Can Increase Risk of Diabetes
A molecule called miR-483-3p is produced at higher levels in individuals who experienced a poor diet in their mother's wombs than those who better nourished.

January 5, 2012--------News Archive

Is Obesity in Infants “Programmed” in the Womb?
Omega 3 fatty acids eaten by pregnant women do not prevent expansive adipose tissue from developing in infants.

Progress Towards a Genital Herpes Vaccine
A vaccine under investigation protected some women against infection from one of the two types of herpes simplex the virus that causes genital herpes.

Rare Liver Disorder Kids Tolerate Mom's Graft Best
Children with a rare, life-threatening disease that is the most common cause of neonatal liver failure – biliary atresia – better tolerate liver transplants from their mothers than from their fathers, according to a UCSF-led study.

January 4, 2012--------News Archive

Simple Blood Test in First Trimester Reveals Gender
New research suggests that measuring the ratio of two enzymes in maternal blood will indicate fetal gender.

Nap-deprived Tots Missing Out On More Than Sleep
Toddlers between 2.5 and 3 years who miss only a single daily nap show more anxiety, less joy and interest and poor understanding of how to solve problems.

Women Susceptible to Infection When Ovulating
High levels of estradiol exist just prior to ovulation and decrease immune system effectiveness which can result in the growth and promotion of infection.

January 3, 2012--------News Archive

Gestational Diabetes Linked To Risk of ADHD
Maternal gestational diabetes mellitus and low socioeconomic status, appear to increase the risk of developing childhood ADHD.

Physical Activity, School Performance May Be Linked
By increasing blood and oxygen flow to the brain, and increasing endorphins which decrease stress, exercise helps improve academic performance.

January 2, 2012--------News Archive

Evolution Reveals Missing Link in DNA/Protein Shape
Despite knowing for the past 50 years that protein folds are determined by DNA sequence, fold shape complexity has limited development of disease treatments.

Bacteria Fights Fluoride in Toothpaste and in Nature
Research has uncovered the molecular tricks used by bacteria to fight the effects of fluoride, commonly used in toothpaste and mouthwash to combat tooth decay.

Gene Identified in Risk for Pancreatic Cancer
Approximately 10 percent of pancreatic cancer patients come from families with multiple cases of the disease. But finding the gene has been difficult.

WHO Child Growth Charts

What Is Your BMI?

       



As the practice of freezing and transferring 'surplus' embryos widens rapidly, concerns about whether the freezing process may interfere with the viability of the embryos are often raised by patients.

A new study highlights that miscarriage is less likely to occur after the transfer of fresh embryos compared with frozen-thawed embryos, and also that the age of the embryos at the time of freezing could influence the miscarriage rate.

The study appears in the December issue of Reproductive BioMedicine Online.

Y.A. Wang and colleagues undertook a retrospective analysis of 52,874 clinical pregnancies recorded on the Australian and New Zealand Assisted Reproduction Database (ANZARD) between 2004 and 2008. The analysis showed that the woman's age and obstetric history are closely related to the risk of miscarriage, but that the transfer of fresh embryos is associated with fewer miscarriages than transfer of frozen–thawed embryos.

The overall miscarriage rate was 18.7%. Younger women (less than 35 years) being almost 3 times less likely to miscarry than women over 40 years of age, and women who had an elective single embryo transfer were less likely to miscarry than if two embryos were transferred.

Transferring thawed embryos which were frozen at an earlier stage of development than the blastocyst were less likely to miscarry. The authors proposed transferring fresh blastocysts and freezing cleavage-stage embryos to reduce the miscarriage rate with IVF and related treatments.

They believe such a practice could lead to a substantial reduction in the miscarriage rate and eliminate much of the anxiety suffered by women undergoing Assisted Reproductive Technology (ART).

As noted by Yacoub Khalaf, Director of the Assisted Conception Unit at Guy's and St Thomas' NHS Foundation Trust, London, in a commentary in the same issue of Reproductive BioMedicine Online, this model for a new practice in ART may have practical limitations and would need to be validated through a randomized trial.

Large databases already collected over past years are rarely free of bias, nor are they comprehensive enough to account for all pertinent variables. Evaluation of this hypotheses in broad randomized trials is necessary for objective validation.

"It is interesting that miscarriage rates of frozen blastocysts were higher in the Australian study, particularly since it is well known that blastocysts have a lower frequency of chromosomal anomalies than cleaved embryos. Blastocyst culture is still a relatively new approach and culture-related factors such as selection for freezing at blastocyst stage may have affected early learning experiences in some clinics. It is therefore important to repeat a similar analysis of Australian clinic data during subsequent years," Dr. Jacques Cohen, senior editor of Reproductive BioMedicine Online, said of the study.

The article is "Transfers of fresh blastocysts and blastocysts cultured from thawed cleavage embryos are associated with fewer miscarriages" by Yueping Alex Wang, Michael Costello, Michael Chapman, Deborah Black, Elizabeth Anne Sullivan (doi:10.1016/j.rbmo.2011.07.023). The article appears in Reproductive BioMedicine Online, Volume 23, Issue 6 (December, 2011), published by Elsevier.

The commentary is "The search for a practice model to reduce miscarriage after assisted reproduction" by Yakoub Khalaf, Tarek El-Toukhy (doi:10.1016/j.rbmo.2011.09.014). The commentary appears in Reproductive BioMedicine Online, Volume 23, Issue 6 (December, 2011), published by Elsevier.

Full text of the article is available to credentialed journalists upon request; contact Greyling Peoples at 31-20-485-3323 or g.peoples@elsevier.com. Journalists wishing to interview the authors may contact Alex Wang at alex.wang@unsw.edu.au.

Reproductive BioMedicine Online was founded by Bob Edwards, the winner of the 2010 Nobel Prize in Physiology or Medicine. It covers the formation, growth and differentiation of the human embryo. It is intended to bring to public attention new research on biological and clinical research on human reproduction and the human embryo including relevant studies on animals.

Elsevier is a world-leading provider of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders.

Original article: http://www.eurekalert.org/pub_releases/2012-01/e-npm010512.php