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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
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June 14, 2012--------News Archive Return to: News Alerts


Women undergoing fertility treatment are usually given daily injections of follicle
stimulating hormone (FSH) to increase the number of eggs
that their ovaries release each month.

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Weekly Fertility Injections Work As Well As Daily

New long-lasting weekly injections of fertility hormones are as safe and effective as standard daily injections, according to new research

The researchers compared weekly and daily hormone injections in a Cochrane systematic review and found no difference in pregnancies or serious side effects between the two regimens.

Women undergoing fertility treatment are usually given daily injections of follicle stimulating hormone (FSH) to increase the number of eggs that their ovaries release each month. In in-vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), the eggs are then removed and fertilised outside the body.

Daily hormone injections can be painful and stressful but a new longer-lasting FSH, known as corifollitropin alfa, has recently been introduced. One injection of this longer-lasting hormone can replace the first seven days of FSH injections required in the standard treatment regimen.

The researchers included data from four trials involving 2,335 people in their review. They show that women given medium doses of the new long-lasting hormone on a weekly basis are equally likely to become pregnant and are no more likely to have a miscarriage or ectopic pregnancy than those receiving daily FSH injections.

"These results show that the new long-acting injections are a safe treatment option and equally effective in medium doses compared to the standard daily injections," said Jan Kremer, one of the authors of the review based at the Radboud University Nijmegen Medical Center in Nijmegen, Netherlands.

However, there is currently limited information about patient satisfaction with long-lasting FSH. "One of the main reasons weekly injections are considered preferable to daily injections is that they are more patient friendly," said Kremer. "So are couples undergoing fertility treatment happier with weekly injections? We would like to see research addressing this question."


Further research is also needed to establish whether long-acting injections are as effective in women who respond poorly to fertility hormones and those who 'hyperrespond', meaning they produce higher than expected numbers of eggs.


Original article: http://www.eurekalert.org/pub_releases/2012-06/w-nwf060812.php