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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
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July 10, 2012--------News Archive Return to: News Alerts


Anatomy of an animal cell.

WHO Child Growth Charts

       

New Target to Fight Cancer Deep Within Cell Nucleus

Investigators have found that blocking a fundamental process deep within cancer cells can selectively kill them and spare normal cells

For more than a century, clinicians have known that abnormalities of the nucleolus—a small, rounded mass within the cell nucleus—can be diagnostic for cancer. The nucleolus is where certain genes are read to form the components of ribosomes, the cellular machines that make proteins. While abnormalities in the nucleolus are known to be diagnostic for cancer, researchers have wondered whether they are required for cells to become malignant.

The work is reported in the July issue of the Cell Press journal Cancer Cell

Now investigators have provided definitive evidence that accelerated reading of ribosomal genes is responsible for causing abnormal nucleoli and is necessary for the survival of cancer cells. They also show that blocking this accelerated reading in mice can set off a cascade of events that cause lymphoma and leukemia cells to die while sparing normal cells.

"The work in this study demonstrates that cancer cells are far more dependent on their ability to make ribosomes than normal cells. Critically, we demonstrate that selective inhibition of the enzyme, RNA polymerase I, that's responsible for synthesizing the major ribosomal components can be used to selectively kill cancer cells while leaving normal cells untouched," says senior author Dr. Ross Hannan, of the Peter MacCallum Cancer Centre in Australia. Previously, it was assumed that the ability to make ribosomes would be equally important to normal and cancer cells.

The findings suggest that selective inhibitors of RNA polymerase I may be effective therapeutics for the treatment of human cancers. Based on the findings in this study, investigators will study one such inhibitor, Cylene Pharmaceuticals' CX-5461, in clinical trials at the Peter MacCallum Cancer Centre later this year.

Bywater et al.: "Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53."

Original article: http://www.eurekalert.org/pub_releases/2012-07/cp-rfn070612.php