Welcome to The Visible Embryo

Home- - -History-- -Bibliography- -Pregnancy Timeline- --Prescription Drugs in Pregnancy- -- Pregnancy Calculator- --Female Reproductive System- News Alerts -Contact

Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



Home

History

Bibliography

Pregnancy Timeline

Prescription Drug Effects on Pregnancy

Pregnancy Calculator

Female Reproductive System

Contact The Visible Embryo

News Alerts Archive
Disclaimer: The Visible Embryo web site is provided for your general information only. The information contained on this site should not be treated as a substitute for medical, legal or other professional advice. Neither is The Visible Embryo responsible or liable for the contents of any websites of third parties which are listed on this site.
Content protected under a Creative Commons License.

No dirivative works may be made or used for commercial purposes.

Return To Top Of Page
Pregnancy Timeline by SemestersFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresFemale Reproductive SystemEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterSecond TrimesterFirst TrimesterFertilizationDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
33333333333333333333333
Google Search artcles published since 2007
 
June 10, 2011--------News Archive

Hormone Test Helps Predict Success In IVF
Women with high levels of the hormone AMH produced more eggs for in vitro fertilization (IVF) procedures, and were more likely to have pregnancies.

Fragile X Protein Acts as Toggle Switch in Brain Cells
Research shows how the protein missing in fragile X syndrome – the most common inherited form of intellectual disability – acts as a molecular toggle switch in brain cells.


June 9, 2011--------News Archive

Early Light Refines the Brain’s Vision Circuitry
Light and sight are connected from the beginning.

Molecule Shared by Nervous and Vascular Systems
IRCM researchers show that a key molecule of the vascular system is essential for the formation of neural circuits.


June 8, 2011--------News Archive

Fetal Exposure to BPA Changes Uterus in Primates
Oral intake of BPA altered expression of HOX and WNT genes which are critical for uterine development.

Pregnancy Weight Gain Risks Fat Baby, Child, Adult
Women who gain too much weight during pregnancy tend to have newborns with a high amount of body fat, regardless of the mother's weight before pregnancy.


June 7, 2011--------News Archive

Exposure to BPA Has Been Underestimated
New research results indicate BPA accumulates more rapidly within the body than previously thought.

Pregnant Women Can Prevent Excess Weight Gain with Simple Steps
Women who did not self-weigh gained an average of 15.2 pounds.


June 6, 2011--------News Archive

Programming Disease by Gender
Excess maternal stress can program adverse health effects through multiple generations, especially in boys.

Birth Control Pill for Men On the Horizon?
But to make the pill a reality, research needs to show that the compound is safe, effective – and reversible.

Finding How Pre-gut Cells Become Focused
Research has outlined exactly how specific cells in sea-urchin embryos become the endoderm, the domain that eventually forms the gut.

Found, Genetic Mutation Causing Excess Hair Growth
Scientists in Beijing, China, have discovered a chromosome mutation responsible for a very rare condition in which people grow excess hair all over their bodies.

WHO Child Growth Charts

Researchers in the Keck School of Medicine of the University of Southern California (USC), together with scientists in Beijing, China, have discovered a chromosome mutation responsible for a very rare condition in which people grow excess hair all over their bodies.

Investigators hope the finding ultimately will lead to new treatments for this and less severe forms of excessive hair growth as well as baldness.

The study, "X-linked congenital hypertrichosis syndrome is associated with interchromosomal insertions mediated by a human-specific palindrome near SOX3," will appear in the June 2, 2011 issue of the American Journal of Human Genetics.

The initial discovery of the mutation came from Zhang's lab, which examined the condition, known as CGH, in a Chinese family. Researchers there worked with Choi to confirm the finding in a Mexican family that Patel first began studying in 1993. Males with this disorder have hair covering their entire face including their eyelids and their upper body, while females have thick patches of hair on their bodies.

"In 1995, we traced the approximate location of the mutation responsible for CGH to a section of the X chromosome in the Mexican family," said Patel, whose laboratory focuses on understanding the genetic basis of inherited diseases.

"We sequenced nearly 100 genes but could not find any mutations. Then recently, Xue Zhang and his colleagues in Beijing were able to pinpoint the exact location, discovering that there was an insertion of chromosome 5 into the X chromosome in the Chinese family. When the Mexican family was examined, a piece of chromosome 4 was found to be inserted into the same part of the X chromosome, thus confirming that these extremely rare events caused the disorder."

The investigators suggest that insertion of the "extra" DNA sequences into the X chromosome apparently turns on a gene, likely SOX3, located near the insertion site. SOX3 is a strong candidate because other members of this gene family have been shown to play a role in hair growth.

In addition, the insertion has occurred within a block of DNA sequence called a "palindrome," in which the sequence of the four building blocks of DNA (akin to letters of the alphabet) read exactly the same as their complementary sequences, but in the reverse direction. The particular palindrome at the site that the researchers studied is only found in humans.

"We don't yet know the significance of the palindromic sequence in this case," Patel said. "But it appears to be unstable, and can be entirely absent in many individuals with normal hair growth. It's only when there is insertion of certain chromosome segments at this site that people have extra hair."

Earlier, researchers had theorized that the CGH mutation is "atavistic" – a trait that reappears after being absent for a long time. One example of an atavistic trait is extra nipples in both men and women.

"It's like the information is there in the genome, but is silenced," Patel said. "Then somehow it's reactivated, and can manifest as the trait. We don't know yet if this is the case with CGH."

Further studies will test if this is indeed true.

"If in fact the inserted sequences turn on a gene that can trigger hair growth, it may hold promise for treating baldness or hirsutism [excessive hair growth] in the future, especially if we could engineer ways to achieve this with drugs or other means," Patel said.

Pragna Patel, professor in the Keck School, the USC Institute for Genetic Medicine, and the Herman Ostrow School of Dentistry of USC, is a co-investigator of the study, and Sunju Choi, a research associate in Patel's lab, is a co-first author. The principal investigator is Xue Zhang, professor and chair of medical genetics at the Peking Union Medical College.