Dec 9, 2013--------News Archive—Latest research covered daily, archived weekly
Gene therapy trial for 'bubble boy' disease promising
Hematopoietic stem cell transplantation (HSCT), once considered an effective yet risky alternative to drug therapy for blood cancer — has become more successful in a wide range of patients due to major advances in transplant strategies and technology.
Survival for stressed mitochondria discovered
Damage to mitochondria is thought to be a significant factor in common neurodegenerative disorders, cancer and even the aging process. Researchers' latest discovery could lead to new methods to protect mitochondria from such damage.
Pinpointing the higher cost of a healthy diet
Harvard School of Public Health Communications (HSPH) study finds it takes $1.50 more per day to eat a nutritious diet rather than an unhealthy one.
Dec 6, 2013--------News Archive—Latest research covered daily, archived weekly
What hummingbirds teach us about using energy
Hummingbird metabolism is a marvel of evolutionary engineering. These tiny birds can power all of their energetic hovering flight by burning glucose and fructose equally.
What yeast teach us about memory formation
Yeast cells are able to form a memory by combining proteins.
What bacteria teach us about division of labor
Bacteria grow faster if they feed each other. When they divide their metabolic labor, they grow faster than bacterial cells that produce all their amino acids on their own.
Dec 5, 2013--------News Archive—Latest research covered daily, archived weekly
Depression in pregnant mom may alter brain in baby
Depression is a serious mental illness that has many negative consequences for sufferers. But depression among pregnant women may also have an impact on the developing brain patterns of babies.
IVF fertility treatments keep multiple births high
Non-IVF treatments are biggeat contributor with ovarian stimulation and ovulation induction. But, fertility technology in the United States has a huge influence on the frequency of twins, triplets, and other multiple births.
Changing cell types by flipping a single switch
With few exceptions, cells don't change type once they have become specialized — a heart cell, for example, won't suddenly become a brain cell. However, new findings by researchers at UC Santa Barbara have identified a method for changing one cell type into another in a process called forced transdifferentiation.
Dec 4, 2013--------News Archive—Latest research covered daily, archived weekly
Prenatal alcohol exposure disrupts brain & behavior
Researchers have long known that ethanol exposure from alcohol impacts brain and cognitive development in infants, but not until now demonstrated the connection between exposure and disruption to neural networks leading to changes in behavior.
'Designer sperm' insert custom genes into offspring
New research suggests altering genes in sperm and then inducing fertilization, produces new genes that are present and active in the embryos and inherited to at least three generations.
'Extreme adaptation' of Burmese python genome
A Burmese python's ability to ramp up its metabolism and enlarge its organs, swallow and digest prey whole, can be traced to an unusually rapid evolution of its genes.
Dec 3, 2013--------News Archive—Latest research covered daily, archived weekly
Air pollution combined with genetics increases risk for autism
Exposure to air pollution appears to increase the risk for autism among people who carry a genetic disposition for the neurodevelopmental disorder.
Male and female mice transfer fear of odor to unborn pups
Researchers find that when a mouse learns to become afraid of a certain odor, his or her pups will be more sensitive to that odor, even though the pups have never encountered it.
Key protein controlling communication between brain cells
Scientists are a step closer to understanding how some of the brain's 100 billion nerve cells co-ordinate their communication.
Dec 2, 2013--------News Archive—Latest research covered daily, archived weekly
High cholesterol fuels growth of breast cancer
A byproduct of cholesterol functions like the hormone estrogen and fuels the growth and spread of the most common types of breast cancers, researchers at the Duke Cancer Institute report.
Fruit flies with better sex lives live longer
Can sexual frustration be bad for your health? Male fruit flies that expected sex — and didn't get it — experienced serious health consequences and aged faster.
Magnesium ion critical in creation of synthetic cell
Investigators working to create "protocells" – primitive synthetic cells – have accomplished an important step towards their goal by identifying that RNA copying requires the presence of the magnesium ion called Mg2+.
Nov 29, 2013--------News Archive—Latest research covered daily, archived weekly
Leukemia cells exploit 'enhancer' DNA to cause disease
Discovery also reveals how a drug, now in multiple human trials, halts production of Myc protein and stops progression of AML.
Dysfunctional mitochondria may be resistant to radiation therapy
The resistance of some cancers to the cell-killing effects of radiation therapy may be due to abnormalities in the mitochondria – the cellular structures responsible for generating energy, according to an international team of researchers.
2-way traffic enables proteins to avoid errors
Messenger RNA may move in more than one direction in order to get the job done.
Nov 28, 2013--------News Archive—Latest research covered daily, archived weekly
Mom's mood affects newborn brain behavior
A great number of women experience depression or anxiety while pregnant, and exposure of their fetus to these maternal mood disorders may lead to long-term emotional and behavioral problems in the child.
Fewer IVF embryo tranfers reduces multiple births, lowering risk, and does not have to increase costs
Research from Belgium has shown that if governments restrict the numbers of embryos transferred during fertility treatment, and combine that restriction with a policy of reimbursing six cycles of assisted reproduction technology (ART), there is no detrimental impact on pregnancy and delivery rates.
What causes pregnancy complications
Researchers at the University of California Los Angeles, have identified a specific type of cell and a related cell communication pathway key to the successful growth of a healthy placenta. The findings could greatly bolster our knowledge about the potential causes of complications during pregnancy.
Nov 27, 2013--------News Archive—Latest research covered daily, archived weekly
Pre-eclampsia rates on the rise in USA
A new study shows an increase of 322% for severe pre-eclampsia.
How the early embryo changes shape
In an early mammalian embryo, just 8-cells large, the roundish cells do something they had never done until that moment – something that would determine whether the embryo survived or failed. They change their shape.
Clue to how the circulatory system is wired
A new mechanism that regulates the way blood vessels grow and connect to each other has been discovered . The knowledge might open up new opportunities for future cancer therapy.
Nov 26, 2013--------News Archive—Latest research covered daily, archived weekly
Steroid injections for premature babies linked to mental health risk
Steroid injections given to pregnant women before premature birth may increase the child's risk of later behavioural and emotional difficulties, a study has found.
Yale team finds clues to origin of autism
Finding major new clues to the origins of autism, a Yale-led team of researchers has pinpointed which cell types and regions of the developing human brain are affected by gene mutations linked to autism.
Antidepressant medication does not increase the risk of autism
New research cannot establish a close connection between the use of antidepressant medication - the so-called SSRIs - during the course of pregnancy and the risk of having a child with autism.
Nov 25, 2013--------News Archive—Latest research covered daily, archived weekly
2 proteins affect how 'jumping genes' - Jump!
Using a new method to catch elusive "jumping genes," research has found two human proteins that are used by one type of DNA to replicate itself and move from place to place.
Nerve Regeneration Following Spinal Cord Injury
Fish, unlike humans, can regenerate nerve connections and recover normal mobility following an injury to their spinal cord.
Cell transplantation cite to treat spinal cord injury
Transplanting neural stem/progenitor cells (NS/PCs) into the spinal cord promotes functional recovery after spinal cord injury (SCI). However, which transplantation sites provide the best benefit?
Nov 22, 2013--------News Archive—Latest research covered daily, archived weekly
Diet alone can be significant source of arsenic
Diet alone can be a significant source of arsenic exposure regardless of arsenic concentrations in drinking and cooking water, a Dartmouth College-led study finds.
PTSD raises risk for obesity in women
Women with PTSD gain weight more rapidly than women without disorder.
The big male nose
Human noses come in all shapes and sizes. But one feature seems to hold true: Men’s noses are bigger than women’s.
Nov 21, 2013--------News Archive—Latest research covered daily, archived weekly
Promiscuous mouse moms bear sexier sons
Male mice make more pheromone if mama had access to many mates.
Found: ancient enzyme that affects DNA repair
The enzyme PrimPol allows cells to make copies of their DNA even when damaged, preventing breaks in the chromosomes.
Aging erodes genetic control, but it’s flexible
Some genes need to be silenced [turned off] for health and long life. Researchers used “reporter” genes to see whether changes associated with aging would reduce fruit flies’ ability to turn off those genes.
Nov 20, 2013--------News Archive—Latest research covered daily, archived weekly
Protein found that regulates burning of body fat
Muscle movements generate body heat. However, body heat can also be generated in another way: body fat contains a small number of brown adipose cells — special fat cells that can generate heat without muscle activity.
New pathway to genetic muscular diseases
Scientists find key gene that activates muscle growth to help improve treatment.
Novel gene therapy works to reverse heart failure
Preclinical testing shows SUMO-1 gene therapy shrinks an enlarged heart, improves heart function, and blood flow.
Nov 19, 2013--------News Archive—Latest research covered daily, archived weekly
Salk scientists make 'mini-kidneys' from human stem cells
Findings may lead to much-needed therapies for kidney disease
New approach to prevent type 1 diabetes
Experimental findings could lead to new, inexpensive therapy using a naturally occurring bile acid.
Bacteria a model for next-generation antibiotics
The recent rise in antibiotic-resistant bacteria is a serious public health threat, and there is a need for new therapeutic strategies to combat these infections.
Nov 18, 2013--------News Archive—Latest research covered daily, archived weekly
Protein interplay in muscle tied to life span
Brown University biologists have uncovered a complicated chain of molecular events that leads from insulin to protein degradation in muscles and significantly diminished life span in fruit flies.
New technique for designing drugs to treat serious illnessResearchers exploit the power of evolution to create designer proteins.
New approach to prevent type 1 diabetes
Experimental findings could lead to new, inexpensive therapy using a naturally occurring bile acid.
Nov 15, 2013--------News Archive—Latest research covered daily, archived weekly
Senescence also plays a role in embryo development
Researchers propose that senescence appeared in embryos as a switch to turn off cells that are no longer useful — not simply at the end of an organism's life. One of the main mechanisms the body uses to protect itself against cancer is to switch off defective cells by making them senescent which stops a cell from dividing.
Potential drug target in sight for rare genetic diseaseResearchers have discovered the structure of a potential drug target for a MPS I (Mucopolysaccharidosis I), paving the way for an alternative treatment for the condition.
A protein that keeps people — and their skeletons — organized
Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it.
Nov 14, 2013--------News Archive—Latest research covered daily, archived weekly
How do cells know to spread to cover and close a wound — or build an embryo? A team of researchers publishes new insights into how epithelial cells manage to spread out and in the case of a wound, cover an injury.
Deleting any single gene provokes mutations
Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism’s genome to compensate, leading to a mutation in another gene.
Retrofitted protein opens door for safer gene therapy
A protein engineered by scientists combines proteins active in HIV and Moloney murine leukaemia virus (MLV) replication and may lead to safer, more effective retroviral gene therapy.
Nov 13, 2013--------News Archive—Latest research covered daily, archived weekly
Moms may pass stress to offspring
Pregnant women may transmit the damaging effects of stress to their unborn child by way of the bacteria in their vagina and through the placenta, suggest new findings from two animal studies.
Of hurricanes, fungus and Parkinson's disease
Scientists at Rutgers and Emory universities have discovered that an organic compound, often emitted by fungi, causes symptoms of Parkinson's disease in fruit flies and may be linked to Parkinson's and other neurodegenerative diseases in humans.
Antidepressant induces juvenile-like state
Brain development and maturation has long been thought to be a one-way process in which plasticity diminishes with age. The possibility that the adult brain can revert to a younger state and regain plasticity may have to be reconsidered.
Nov 12, 2013--------News Archive—Latest research covered daily, archived weekly
Pregnant exercise boosts newborn brain development
As little as 20 minutes 3 times per week is enough to enhance brain activity.
What are you scared of?
What makes mice freeze with fear? A neural switch was discovered using the same neuron-blocking technique, indicating different brain regions process different types of fear. The discovery could have implications for phobias and panic attacks.
mTOR pathway could lead to glioblastoma treatment
Investigators at Johns Hopkins have found a known genetic pathway to be active in many difficult-to-treat pediatric brain tumors called low-grade gliomas, potentially offering a new target for the treatment of these cancers.
Nov 11, 2013--------News Archive—Latest research covered daily, archived weekly
Edited RNA + invasive DNA adds individuality
An enzyme that edits RNA may loosen gene control over invasive snippets of DNA and affect how genes are turned on and off. In fruit flies, this newly understood mechanism appears to contribute to differences in individual eye color and life span.
Protein guides production of DNA into RNA
Scientists at the Gladstone Institutes are shedding light on key aspects of transcription, thus coming even closer to understanding the importance of this process in the growth and development of cells—as well as what happens when this process goes awry.
New explanation for infection susceptibility in newborns
Cells that allow helpful bacteria to safely colonize the intestines of newborn infants, also suppress their immune systems to make them more vulnerable to infections.
Nov 8, 2013--------News Archive—Latest research covered daily, archived weekly
Endometriosis risk linked to two pesticides
The Fred Hutchinson Cancer Research Center has found that two organochlorine pesticides are associated with an increased risk of endometriosis, a condition that affects up to 10 percent of reproductive-age women.
Fountain-of-youth gene repairs tissue in adults
Young animals recover from tissue damage better than adults, and from Charles Darwin's time until now, scientists have puzzled over why. A recent study reveals that the Lin28a gene, which is very active in embryos but not in adults, enhances tissue repair after injury when reactivated in adult mice.
Mechanism found making ordinary stem cells — tumors
Epigenetic effects on cell signaling leads healthy stem cells to create benign fibromas in the jaw, which could become harmful.
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